Differential activation of Staphylococcus aureus

نویسندگان

  • Catherine A. Wakeman
  • Devin L. Stauff
  • Yaofang Zhang
  • Eric P. Skaar
چکیده

3 Catherine A. Wakeman, Devin L. Stauff, Yaofang Zhang, and Eric P. Skaar 4 5 6 7 8 9 10 11 1 Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, 12 Nashville, TN, USA 37232, 2 Current address: Department of Biology, Grove City College, Grove City, 13 Pennsylvania, USA 16127 14 Running title: Toxic heme analogues activate S. aureus HssRS/HrtAB 15 16

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The role of Staphylococcus superantigens in chronic plaque type psoriasis

Background: T cell activation is discussed as an important factor in the pathogenesis of psoriasis. Recently, a lot of attention has been paid to the role of superantigens in T cell activation in the pathogenesis of psoriasis. In this study, the role of staphylococcal superantigens in the pathogenesis of psoriasis with identification of staphylococcal toxin levels in the skin lesions of p...

متن کامل

Toll-like Receptor (TLR) Signaling and Differential Activation of PGC Family Genes in a Mouse Model of Staphylococcus aureus Sepsis

Toll-like Receptor (TLR) Signaling and Differential Activation of PGC Family Genes in a Mouse Model of Staphylococcus aureus Sepsis by Timothy Elisha Sweeney Department of Pathology Duke University Date:____5/20/2010________ Approved: ___________________________ Claude A. Piantadosi, MD, Supervisor ___________________________ Soman N. Abraham, PhD ___________________________ Salvatore V. Pizzo,...

متن کامل

A modulatory interleukin-10 response to staphylococcal peptidoglycan prevents Th1/Th17 adaptive immunity to Staphylococcus aureus.

Toll-like receptor (TLR) 2 on antigen-presenting cells (APCs) enables these cells to recognize peptidoglycan-embedded lipopeptides and glycopolymers in the Staphylococcus aureus cell wall and mount an inflammatory response to this microbe. TLR2 signalling can also modulate immunity to S. aureus by inducing an interleukin (IL)-10 response in APCs. What determines the balance between proinflammat...

متن کامل

RNA-Seq Reveals Differential Gene Expression in Staphylococcus aureus with Single-Nucleotide Resolution

Staphylococcus aureus is a gram-positive cocci and an important human commensal bacteria and pathogen. S. aureus infections are increasingly difficult to treat because of the emergence of highly resistant MRSA (methicillin-resistant S. aureus) strains. Here we present a method to study differential gene expression in S. aureus using high-throughput RNA-sequencing (RNA-seq). We used RNA-seq to e...

متن کامل

Differential response of bovine mammary epithelial cells to Staphylococcus aureus or Escherichia coli agonists of the innate immune system

Mastitis caused by Escherichia coli and Staphylococcus aureus is a major pathology of dairy cows. To better understand the differential response of the mammary gland to these two pathogens, we stimulated bovine mammary epithelial cells (bMEC) with either E. coli crude lipopolysaccharide (LPS) or with S. aureus culture supernatant (SaS) to compare the transcriptomic profiles of the initial bMEC ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014